The Video discusses some profound questions that humans ponder. It starts by addressing a brother who has stopped breathing and is thirsty. It advises the brother to start breathing first before anything else, as stopping breathing will lead to death within 3-5 minutes, making any other needs like water irrelevant. It then poses some of the most profound questions humans contemplate - questions about predestination, how the human mechanism works, and fundamentally, whether there is a creator. It asks why one should believe in a creator and believe in the existence of this almighty being. It states that if a creator's existence cannot be proven as a fact, then all of these questions are irrelevant anyway.